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Advanced fibrosis (stage 3) is associated with a higher risk of developing hepatic decompensation (ascites, variceal bleeding, and hepatic encephalopathy), need for liver transplantation, and increased mortality
A study found that while the drug is effective in weight management throughout therapy, discontinuing use will result in the patient regaining weight

GLP-1 Receptor Stimulation of the Lateral Parabrachial Nucleus Reduces Food Intake: Neuroanatomical, Electrophysiological, and Behavioral Evidence

A.BergmanA.StevensC.KoteyP.YiB.ZhaoP.et al (2006a)

doi: 10.1177/1479164118825376
