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Most treatment plans begin at 0.25 mg once weekly, remain at that dose for four weeks, then increase by 0.25 mg each month until reaching a maintenance dose
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GLP-1R is expressed in cardiomyocytes and coronary endothelium, and sema has been studied in cardiac ischemia-reperfusion models and inflammation paradigms to characterize cardioprotective signaling pathways at the molecular level
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