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Amylin stimulates plasma renin concentration in humans

GLP-1 levels naturally increase after eating meals high in protein and fiber

The role of GLP-1R in DM is principally to regulate glycemic control by stimulating insulin secretion, inhibiting glucagon secretion, and improving insulin signaling, thereby reducing blood glucose levels
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Activation of the GLP-1R stimulates the PI3K/Akt/mTOR pathway, which in turn upregulates the expression of antioxidant enzymes and reduces ROS production
