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how were glp-1 drugs discovered The revolution: What UAB researchers are discovering about these work The GLP-1 revolution: What UAB

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how were glp-1 drugs discovered The revolution: What UAB researchers are discovering about these work The GLP-1 revolution: What UAB

Key milestones highlighted in this timeline: 1999 Orlistat (Xenical) The first long-term FDA-approved anti-obesity medication of the modern era

how were glp-1 drugs discovered The revolution: What UAB researchers are discovering about these work The GLP-1 revolution: What UAB

GLP-1 levels correlate with disease severity

how were glp-1 drugs discovered The revolution: What UAB researchers are discovering about these work The GLP-1 revolution: What UAB

Eli Lilly have a new, once-monthly GLP1/GIP agonist (Brenipatide) and they're running some fascinating trials with it Smoking cessation, bipolar disorder, schizophrenia, opioid use disorder, depression, alcohol use disorder, and asthma

how were glp-1 drugs discovered The revolution: What UAB researchers are discovering about these work The GLP-1 revolution: What UAB

Interestingly, glucagon-like peptide-1 receptor agonists (GLP-1RAs), used in the treatment of T2DM and obesity, are known to show pro-cognitive and neuroprotective properties, and exert modulatory effects on immune, endocrine and metabolic processes in the central nervous system

how were glp-1 drugs discovered The revolution: What UAB researchers are discovering about these work The GLP-1 revolution: What UAB

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