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The rapid increase in the use of these medications has led to supply challenges and resulted in the proliferation of compounded analogs, raising concerns about safety and bioequivalence [45]

9 Study Differences: There is considerable variation (heterogeneity) in reported results across studies

Prefilled pens may allow for slightly longer storage because the sealed delivery mechanism reduces air exposure compared to multi-dose vials

12 weeks (3 vials): 7.2 mL 1 10 mL bottle 24 weeks (9 vials): 21.6 mL 3 10 mL bottles 48 weeks (21 vials): 50.4 mL 6 10 mL bottles Alcohol Swabs One for the vial stopper + one for the injection site each week