what was the first glp 1 drug glp-1 GLP-1s for Weight Loss: You Need to Know New GLP-1 Guidelines for Type

The time and severity of seizures induced by systemic administration of the neurotoxin kainic acid is enhanced in GLP-1R KO mice relative to WT controls whereas the destructive effect of kainic acid is ameliorated in the GLP-1R KO mice upon targeted AAV-mediated restoration of hippocampal GLP-1R expression [417]

This is likely because GLP-1 agonists can delay the emptying of bile from the gallbladder

Because of how annoying these side effects are, patients may not take their medication as prescribed [195]

Some research suggests GLP-1 medications may benefit patients with cardiovascular disease by lowering blood pressure, improving cholesterol, and reducing inflammation

Other adverse effects, including depression, sleep disturbances, and anxiety, have also been noted