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Combination Therapy: While low-risk on their own, GLP-1 RAs increase hypoglycemia risk when combined with insulin or sulfonylureas

We delineate how systemic metabolic dysfunction, often associated with obesity, synergizes with local inflammation to alter the balance between MMPs and their tissue inhibitors TIMPs, thus contributing to a perpetuating circle of inflammation and fibrosis

We cover common side effects such as nausea, vomiting, diarrhea, and constipation, affecting 40-70% of users

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