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Sources: Semaglutide (Ozempic): How It Works & Side Effects | Cleveland Clinic 19 Side Effects of Semaglutide for Type 2 Diabetes (Ozempic) and Weight Loss (Wegovy) | Good RX Semaglutide: Double-edged Sword with Risks and Benefits | PMC

These receptors influence appetite signaling, nutrient absorption, insulin sensitivity, and hepatic glucose production

Poor sleep increases cortisol and ghrelin (the hunger hormone) while reducing leptin signaling, counteracting semaglutide's appetite-suppressing mechanism

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If youve recently started a new workout routine or increased your activity, this could be the cause