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The 1-2% impurity fraction at this level is typically dominated by a single major impurity class rather than a mixture, which makes it more predictable and controllable

PMID: 35148829 ACS Med Chem Lett In Vitro Characterization of Agonist and Antagonist Peptide Binding Interaction Kinetics to GLP-1R in HEK293T Cells Using Surface Plasmon Resonance Microscopy

Tirzepatide, a dual glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist initially approved to treat type 2 diabetes, has demonstrated therapeutic potential as a safeguard against the adverse effects of doxorubicin

The question of whether 20 units is too much also depends on your concentration and prescribed dose

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