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Serotonin and GLP-1 agonists While the interaction between GLP-1 and serotonin within the central nervous system is an emerging area of research, it is known that GLP-1 receptors are particularly concentrated in the nucleus tractus solitarius (NTS), a structure in the brainstem responsible for key homeostatic functions, including appetite regulation

The 10mg dose falls between these benchmarks

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As previously reported, the reduction of inflammation may be related to weight loss, that was significant in the different outcome trials, going from a 0.6-kg reduction at 12 weeks with Lixisenatide in ELIXA trial to 4.3 kg at 2 years with injectable semaglutide in SUSTAIN-6 trial [25, 26]

Adelaide, 2022