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Karsdal (Nordic Biosciences, Denmark) for assistance with circulating collagen fragment detection and interpretation
Several plausible explanations include: insufficient autophagy suppression in patient tumors by HCQ, the dual role of autophagy inhibition in suppressing tumor metabolism and proliferation while potentially promoting metastasis, and the current lack of suitable pharmacodynamic biomarkers (66, 106, 107)
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These effects are more likely to happen in people who already have risk factors
