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Step 5: monitor your response during the transition During the first four to six weeks after switching, pay attention to these markers: Appetite changes: Most people notice appetite suppression returning or intensifying within the first two weeks on tirzepatide, even at the starting 2.5mg dose

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Consequently, individuals in a state of decreased basal dopamine signaling, known as a hypodopaminergic state, may possess a greater risk for post-GLP-1RA treatment-associated psychiatric conditions such as depression and suicide, where polymorphisms in the DRD2 receptor are likely implicated in this pathophysiology [160,161]

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Introduction Embarking on a weight loss journey often comes with a blend of hope and questions