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Caffeine, Nausea, and GLP-1 Side Effect Overlap Both caffeine and semaglutide can trigger nausea, especially on an empty stomach or in high doses

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In the clinical experience of the authors, such effects tend to be variable in terms of severity and usually resolve with continuous use

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These symptoms could indicate a more serious condition, and prompt medical evaluation is essential for your safety within your medically supervised TrimRx program