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Calibrate Founded: 2020 Total funding: $127.6 million What Calibrate does: Calibrate, based in New York, offers a weight-loss program it calls "Metabolic Reset" that uses a combination of GLP-1 prescriptions and twice-monthly virtual coaching sessions to help members make changes to their diets, exercise routines, and other habits

"Women who thought that they could never get pregnant, if you're treating them with these medicines, they might, so we just have to be very careful with educating on the risks." The FDA said in a report that there is insufficient data on the effects of these drugs on pregnant patients

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