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Orlistat (Xenical, Alli) reduces fat absorption in the gut and is the only effective over-the-counter weight loss pill available, says Johnson-Rabbett, though it can have significant gastrointestinal side effects

Serious adverse events including pancreatitis and gallbladder disease have been reported at lower rates across clinical trial populations

Women tend to notice this sooner and more acutely than men, partly because women typically start with longer hair that makes shedding more visible, and partly because the female demographic is disproportionately affected

For the first time, clinicians have pharmacological agents that demonstrate meaningful efficacy in a condition that was previously challenging to treat

These potential benefits, however, come with high costs that raise concerns about the impacts on public and private payers