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( 10.1016/j.molmet.2021.101351) [DOI] [PMC free article] [PubMed] [Google Scholar] Drucker DJ & Holst JJ

This dosage is typically reached after gradually increasing the dose over time and is ideal for patients who have successfully adjusted to the medication

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Just recently, in 2024, publications covering this critical topic reached emergency room clinicians

Because they act through non-overlapping mechanisms, some protocols examine them in combination or parallel though combination research should have a clear mechanistic rationale