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Retatrutide adverse events comparable to established GLP-1 drugs Across both studies, adverse events were consistent with those of existing GLP-1 therapies, with reports of nausea, diarrhea, and vomiting generally increasing in groups receiving higher doses

Ania Jastreboff, MD, PhD, has co-authored numerous research studies on dual- and triple-receptor hormone agonists, including retatrutide

The gastrointestinal tolerability profile of tirzepatide generally improves over time as the body adapts to the medication, though individual responses vary considerably

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