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[1] [2] The SUSTAIN-6 trial showed that semaglutide may reduce the risk of major adverse cardiovascular events in people with type 2 diabetes and established cardiovascular disease, though this is not a licensed indication in the UK

AZD9550 and LY3305677 are GLP-1R and GCGR dual agonists in the early stages of clinical trials, being investigated as novel therapeutic options for the treatment of obesity

Similarly, the dropout rate from ketogenic diets compared to control diets requires further investigation, as it varies significantly across studies, ranging from 13% to 84% [261]

All medications come from licensed 503A compounding pharmacies, and PlexusDx serves all 50 states without requiring insurance or membership fees

Some users see reduced appetite and weight loss within 12 weeks , but visible results generally appear within 812 weeks with consistent use and lifestyle support