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Sourris KC, Ding Y, Maxwell SS et al (2024) Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products-induced inflammation
Ideal candidates are those with realistic expectations about what they can achieve with medically-supervised weight loss treatments such as tirzepatide
In addition, researchers determined that participants taking retatrutide had not yet reached a weight loss plateau at 80 weeks, meaning continued treatment would likely produce further weight loss
Therapeutic innovation now includes dual and triple incretin receptor agonists [4,5,6,7] as well as orally bioavailable small-molecule formulations [8, 9], reflecting ongoing efforts to enhance pharmacodynamic durability
Hay M, Thomas DW, Craighead JL, et al
