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If you lose 20 pounds and 10 of it is muscle, you have successfully lowered your metabolic rate and your metabolic reserve thereby ensuring that you will regain the weight later, and increased your risk of frailty
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Chronic Testosterone Treatment Induces Selective Insulin Resistance in Subcutaneous Adipocytes of Women
doi: 10.1016/j.physbeh.2016.12.034
