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Preclinical research in rodent models has consistently demonstrated that GLP-1 receptor activation reduces voluntary alcohol intake, decreases alcohol-seeking behaviour, and attenuates alcohol-induced dopamine release in reward centres of the brain

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The lack of a Fab7F38 effect on GLP-1 mediated cAMP production was tested in H293T stably overexpressing SNAP-tagged human GLP-1R (the plasmid purchased from Cisbio)

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