glp-1 agonists mechanism of action of GLP-1 Receptor Agonists as Treatments
Description
As noted by others (Khan et al., 2020), it remains to be clarified if use of GLP-1 RAs is safe across the HF phenotypes

They are primarily prescribed for managing chronic metabolic conditions like Type 2 diabetes and clinical obesity

Hales C, Carroll M, Fryar CD, et al

Exercise remains a cornerstone of obesity management, and combined exercise with GLP-1RA therapy can support weight maintenance [49]

NE from sympathetic nerves passes into the intestinal lumen We used a Ussing chamber to investigate whether the NE concentration on the mucosal side of the cecal tissue was increased by administration of drugs to the serosal side
