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Addressing Metabolic Dysfunction as an Independent Cancer Risk Factor Accumulating evidence positions metabolic dysfunction characterised by insulin resistance, hepatic steatosis, dyslipidaemia, and visceral adiposity as a more powerful and proximate predictor of cancer risk than elevated body weight alone
Diabetes Care 2019;42:S90-S102
This effect has been observed both in vitro and in vivo
"What we saw was that this group was gaining weight, and what they gained was fat." Scientists said the drug appeared to become less effective after interruption, even after the mice got back on for a second cycle and stayed on consistently for 62 days
We measure the odds ratio of developing pancreatitis between patients who have taken a large cumulative dose of GLP-1 agonist and those with a low cumulative dose of GLP-1 agonist
