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Aspirin Generic Name: Acetylsalicylic acid, ASA Drug Class: NSAID Mechanism of Action: aspirin (acetylsalicylic acid) acetylates a serine residue in the active sites for both COX-1 & COX-2, which irreversibly inhibits these enzymes (as illustrated for COX-1 in Figure 1)

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Manu Chakravarthy, who oversees cardiovascular, renal, and metabolism product development at Roche, said the company must consider the full range of people living with obesity because the condition is heterogeneous, complex, and will require segmentation

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