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We want people who need these medications to be able to access them, he said

This reduction causes afferent arteriole vasodilation, increasing the glomerular filtration rate

36,37 It is debated whether this effect might trigger ventricular and atrial tachyarrhythmias

In conclusion, both SGLT2-i and GLP1-RA seem to have several effects on RAAS, though additional studies are needed to clarify this relationship
