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Supply Shortages: Due to increased demand, theres been a shortage of semaglutide injection products (Ozempic and Wegovy) since 2022

doi: 10.1152/ajpregu.00520.2015 29 RehfeldJFKnopFKAsmarM

Thyroid tumors: Semaglutide comes with an FDA boxed warning about a possible risk of thyroid C-cell tumors
has served as a consultant for Novo Nordisk and Viking Therapeutics, and serves as a national lead investigator or on the executive committee for trials conducted by AstraZeneca and Novo Nordisk

Patients should avoid extreme temperature changes when possible and be particularly cautious in cold weather, as reduced cold tolerance may increase risk of hypothermia during prolonged exposure