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Assuming a 10% incidence of the primary endpoint and a 15% relative risk reduction, the statistical power to detect a significant difference with just 277 patients would be only 11%
doi: 10.1185/030079908X253870 6 GaspariTLiuHWelungodaIHuYWiddopREKnudsenLBet al
Altered zonal expression of the CD26 antigen (dipeptidyl peptidase IV) in human cirrhotic liver

This foundational step helps identify any potential contraindications before a prescription is even considered
