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In recent years, glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as cornerstone therapies in the management of T2D and obesity [57]

Semaglutide (Ozempic and Wegovy) resulted in a 14.9% reduction in body weight in clinical trials, while tirzepatide (Mounjaro and Zepbound) led to a 20.9% body weight reduction

Preparing the patient for what to expect fosters realistic expectations, builds trust, and encourages adherence to therapy

Y-WF: Methodology, Writing review & editing

Efficacy and safety of antidiabetic agents for major depressive disorder and bipolar depression: a meta-analysis of randomized, double-blind, placebo-controlled trials