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The initial mention is chuckle-worthy, as well as the jingle riff of Oh, oh, oh, its Lizzo! However, the joke doesnt seem quite as topical or punch the way Matt and Trey are known for

They occur because the body undergoes metabolic adaptation, reducing its resting metabolic rate as it adjusts to a lower caloric intake and reduced body mass

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If youve had several episodes of depression, the condition is more likely to come back if you stop taking antidepressants