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Julie Joseph Feb 4, 2025 4 min read Obesity and Type 2 Diabetes has an increasing prevalence worldwide, presenting a major health challenge

Limitations Despite these strengths, several limitations must be acknowledged

Oral GLP-1 therapy is quickly reshaping how we treat type 2 diabetes, especially for patients who hesitate at the thought of injections
Mazdutide needs longer-term data at higher doses to demonstrate comparable sustainability

Leg cramps are not listed as a recognised adverse effect in UK Summaries of Product Characteristics for GLP-1 receptor agonists
