glp 1 agonist dosing Are Serious Anesthesia Risks of Semaglutide and Other GLP-1 Agonists Under-Recognized? Case Reports of Retained Solid Gastric Contents in Patients Undergoing Anesthesia Comparison of GLP-1-receptor agonists |

These medications exert (in)direct hepatic actions by reducing steatosis, attenuating inflammation, and potentially reversing fibrosis, while simultaneously addressing systemic metabolic abnormalities including excessive obesity, insulin resistance, and cardiovascular risk

ACC/AHA guideline update for perioperative cardiovascular evaluation for noncardiac surgery--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1996 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery)

As other drug companies started to see the potential of these peptides, they started tweaking them like chemists playing with Legos

10.1111/dom.15636 [DOI] [PMC free article] [PubMed] [Google Scholar] 60.Magruder ML, Miskiewicz MJ, Rodriguez AN, Mont MA (2024) Semaglutide use prior to total hip arthroplasty results in fewer postoperative prosthetic joint infections and readmissions

Future research should evaluate the impact of GLP- 1 RA on sarcopenia in high-risk patient populations