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LLYs forward P/E contracted from 35.55x in March 2025 to 25.90x today, per TIKR data, reflecting the markets recalibration of GLP-1 growth expectations rather than any deterioration in the business itself

The benefit emerged within three months of initiation

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For patients who have plateaued on semaglutide, a provider may consider whether transitioning to tirzepatide is appropriate

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