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The physiological actions of endogenou...

We also describe the development of incretin-based pharmacotherapy, starting with exendin- 4 and ending with the identification of multi-incretin hormone receptor agonists, which appear to be the next major step in the fight against T2DM and obesity

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This landmark policy change recognises obesity as a chronic disease and recommends that GLP-1 antagonists are used by adults for the long-term treatment of obesity

95% CI 0.94, 1.03)