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While Retatrutide has relatively few drug interactions, the slowed gastric emptying can affect absorption of other oral medications

As a consequence, there are major implications for the affected individuals quality of life and also for society, including healthcare costs

Still, Gendreau says these products are no better than ultra-processed foods

Nutrients 2019;11:2704

A recent study investigated the effects of GLP-1R agonists in a multi-hit mouse model in which the combination of a high-fat diet and angiotensin II-induced a cardiometabolic HFpEF phenotype that resembles the human HFpEF phenotype to a large extent characterized by obesity, impaired glucose handling, and metabolic dysregulation accompanied by inflammation