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[PubMed] [Google Scholar] 5.Ohneda A., Parada E., Eisentraut A

People With Specific Medical Conditions If you have a history of pancreatitis, gallbladder disease, severe gastroparesis (delayed stomach emptying), medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2), discuss these conditions with your doctor
GI symptoms resurface: Nausea, constipation, and diarrhea commonly return during tirzepatide initiation, consistent with starting any new GLP-1 treatment

There is no licensed pharmacological treatment specifically for NAFLD in the UK at present, though several therapeutic approaches are under investigation

Why Triple Agonism Matters Rather than observing one isolated pathway, investigators can evaluate how three interconnected hormonal systems influence one another
