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2018;136(Pt B):343-349

Phase III results for retatrutide are set to be released later in 2025 and in early 2026, but an earlier phase II trial recorded between a 7.2% and 17.5% reduction in body weight after 24 weeks, depending on the dose (7.2% on 1mg, 17.5% on 12mg), and up to a 24.2% reduction in body weight after 48 weeks for those on 12mg (-8.7% change for those on 1mg) 8

This means that out-of-pocket premium costs for ACA marketplace enrollees will increase by more than 75 percent, meaning many healthier enrollees could drop their coverage, which can, in turn, increase the cost of premiums
The supplement can also interfere with lab work you may need to rule out underlying causes, especially when it comes to thyroid enzymes

These medications work primarily by slowing the digestive process and suppressing hunger, making it easier for you to make healthier eating choices
