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[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Yang J, Ren J, Song J, Liu F, Wu C, Wang X, et al
Patients have also reported challenges tied to rapid weight loss, including loose or sagging skin, muscle loss and the return of or emergence of eating disorder symptoms.

Initial Dosing and Titration Starting Dose: 2.5 mg injected subcutaneously (under the skin) once a week
Pale straw-coloured urine indicates adequate hydration, whilst darker yellow suggests you may need to increase fluid intake, particularly if experiencing gastrointestinal side effects
