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GLP-1 receptor activation exerts profound systemic effects that indirectly benefit hepatic steatosis and MASH through multiple complementary mechanisms

By: Kristin Brooks Managing Editor, Contract Pharma For pharma manufacturers, the growth of GLP-1 drugs to treat conditions such as diabetes and obesity has placed increased strain on the supply chain and subsequent pressure to avoid bottle necks

Researchers suggest these drugs might be toxic to the kidneys when combined with other medications such as non-steroidal anti-inflammatories for pain relief

Its action is mediated by receptors expressed by the endocrine pancreatic B-cells