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Germ-free (GF) mice, devoid of any microbiome, can provide valuable insight into the impact of the gut microbiome on host metabolism

It can also restrict a persons activity and mobility, which in turn can exacerbate problems that tend to diminish health and quality of life in older adults problems such as social isolation, depression, and muscle loss, known as sarcopenia
Association of aspirin use with reduced risk of developing Alzheimers disease in elderly ischemic stroke patients: a retrospective cohort study

By aiding weight loss, improving glycemic control, and potentially even directly acting on fat cells and the cardiovascular system, these medications may contribute to improved metabolic profiles
