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A landmark study demonstrated gut microbiome diversity decreased activation across four major immune cell types (CD4+ T cells, CD8+ T cells, B cells, and monocytes), alongside reductions in 19 circulating inflammatory proteins, including IL-6

The complete semaglutide versus tirzepatide comparison covers efficacy differences across all outcomes, not just mental health

However, unlike natural GLP-1, which breaks down quickly in the body, semaglutide is designed to stay longer in circulation allowing once-weekly dosing

For long-term preservation of molecular integrity, we recommend storing lyophilised vials in a designated laboratory freezer at -20C

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