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In this review, we discuss the discovery and development of the first rationally designed approach to unimolecular co-agonism, which recruits the well-established pharmacology of glucagon-like peptide 1 (GLP-1) and, counterintuitively, glucagon

The susceptibility of neurons to mitochondrial dysfunction may be explained by the high dependence of neurons on oxidative phosphorylation (69)

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When commercially available options are limited, compounding offers flexibility in formulation and administration