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A subsequent Japanese survey ( N = 500) also assessed the willingness of patients with T2D to initiate different GLP-1RA therapies based on unbranded therapy profiles
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Phase 2 Trial Results (NEJM 2023) The landmark Phase 2 trial enrolled 338 adults with obesity (BMI 30) or overweight with comorbidities (BMI 27) but without diabetes
Functional studies revealed that activation of GLP-1R in the PVN reduces food intake (Larsen et al., 1997
