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Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have transformed the therapeutic landscape of type 2 diabetes (T2D) and obesity by offering substantial weight loss and cardiometabolic protection

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Tirzepatide activates two hormone pathways to lower blood sugar and support weight loss in prediabetes

The primary outcome was change in HbA1c from randomisation to the end of treatment, secondary outcomes included body weight change
