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93 Based on mouse models, where the glucagon gene was disrupted by the insertion of green fluorescent protein, abolishing the synthesis of its products, including GLP-1

This further supports the theory that the central and peripheral GLP-1 systems are not only anatomically but also functionally distinct

HRT is widely prescribed in primary care women with obesity are most likely to be using a transdermal (TD) form of oestrogen, which will not be affected by a GLP-1 agonist

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