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Exposure to 40C or above can destroy the peptide within hours
doi: 10.2337/dc11-s231 [DOI] [PMC free article] [PubMed] [Google Scholar] 28
Thus, the integrity of the hiatus depends upon the structures bridging the gap between the esophagus and the surrounding crural diaphragm making the detailed anatomy of this area of prime importance
It is not genetics, though genetics play a role
