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Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), also known as multiorgan hypersensitivity, has been reported in patients taking topiramate

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Further long-term, randomized controlled trials across diverse populations are necessary to definitively establish Berberines clinical effectiveness, optimal dosage, and long-term safety profile in managing metabolic health and obesity

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This feature enables T cells to be quickly activated in response to molecular signals from infections or tumors, causing the synthesis of considerable volumes of inflammatory-promoting cytokines and chemokines [153, 154]