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Patients taking insulin and insulin secretagogues: consider decreasing the dose of these medications when starting tirzepatide

Family members of patients diagnosed with Fabry disease should be screened based on the inheritance pattern

The optimal dose depends on the formulation, enhancement strategy used, and research objectives

In the diabetes trial published in The Lancet in June 2026, retatrutide as a first drug drove blood sugar to near-normal levels in early type 2 diabetes while taking off 15.3 percent of body weight

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