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For IBS-like discomfort more broadly, the 2021 American College of Gastroenterology clinical guideline on IBS made a conditional recommendation against the use of probiotics for the treatment of global IBS symptoms, citing very low quality of evidence and substantial heterogeneity across strains, doses, and outcomes.[6] The ACG position is the strongest authoritative reading available

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2.2.3 Type III cells They have structural features shared with the other two types of cells, representing 15% of total TRCs (50)

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