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The renal medulla, whose blood flow is tightly regulated to maintain the interstitial medullary osmotic gradient, is highly vulnerable to ischemic injury
It is not appropriate for everyone, and understanding who benefits most helps researchers make informed decisions about whether the added complexity and cost are justified
10.1038/s41581-024-00820-6 9 FrasJ
Rotating injection sites helps prevent this
doi: 10.1016/j.diabres.2021.109119
