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In our estimation, the potential of superior potency of nimacimab in this disease state may offer the widest possible therapeutic window among CB1 inhibitors. Figure 2 - Comparison of potency between monlunabant* and nimacimab** * Monlunabants potency dropped significantly at high agonist levels due to direct competition for the receptors orthosteric site
Being licensed means the MHRA has assessed these drugs as safe and effective for certain medical purposes
In people, small trials and observational work show signals
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